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Innovative Research成立于1998年,因为我们意识到难以获得可靠,高质量和价格合理的研究材料。 从人类血浆和血清等核心产品开始,Innovative Research已发展成为所有实验室试剂的可靠供应商,包括人类生物制品和ELISA试剂盒。今天,我们生产和供应超过3,000种高品质的人类和动物生物,包括血浆,血清,组织和蛋白质。2007年,我们在密歇根州诺维建造并搬入了我们最先进的设施(如下图所示),以适应我们不断增长的产品线。
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Innovative Research/Mouse TREM-1 ELISA Kit/IRKTAH5471/1 Ea

  • 产品编号: IRKTAH5471
  • 美  元  价: $495.00
  • 会  员  价: 待定
  • 品       牌: Innovative Research
  • 产       地: 美国
  • 公       司: Innovative Research
  • 产品分类: ref="." class="index">首页 > Innovative Research/Mouse TREM-1 ELISA Kit/IRKTAH5471/1 Ea
  • 公司分类: Assay and ELISA Kits
Size:1 Ea
Innovative Research/Mouse TREM-1 ELISA Kit/IRKTAH5471/1 Ea
  • Innovative Research/Mouse TREM-1 ELISA Kit/IRKTAH5471/1 Ea
商品介绍

Product Description

Mouse TREM-1 ELISA Kit - 1 Kit (96 Wells)
Our Mouse TREM-1 ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse TREM-1 in cell culture supernates, serum and plasma (heparin, EDTA), cell lysates and tissue homogenates.

Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide(LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8(IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1(MCP1, or SCYA2) and tumor necrosis factor(TNF); MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules(e.g., ITGB1) and costimulatory molecules(e.g., CD40). Trem1 is associated with DAP12(TYROBP), a molecule frequently associated with activating receptors.

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品牌介绍

Innovative Research成立于1998年,因为我们意识到难以获得可靠,高质量和价格合理的研究材料。 从人类血浆和血清等核心产品开始,Innovative Research已发展成为所有实验室试剂的可靠供应商,包括人类生物制品和ELISA试剂盒。

今天,我们生产和供应超过3,000种高品质的人类和动物生物,包括血浆,血清,组织和蛋白质。

2007年,我们在密歇根州诺维建造并搬入了我们最先进的设施(如下图所示),以适应我们不断增长的产品线。



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